Íscia Lopes-Cendes

Universidade Estadual de Campinas – Campinas, Brasil.

Departamento de Genética.

LECTURE: New Avenues in Molecular Genetics for Diagnosis and Therapeutics, as Applied to the Epilepsies.

The development of the cerebral cortex involves complex steps, requiring tightly regulated molecular mechanisms for the efficient and precise control of gene expression. Some of the molecular pathways that control gene expression are mediated by microRNAs, a class of noncoding RNAs that regulate gene expression at the posttranscriptional level.

Gene regulations mediated by microRNAs have emerged as potential regulators of numerous biological processes within the brain, especially in neurodevelopment. In her lecture Iscia Lopes-Cendes will discuss the use of molecular genetics as a possible target for diagnosis and therapy in neurological diseases such as epilepsy.